The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
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Deposition and atomic drive microscopy of particular person phthalocyanine polymers involving nanofabricated electrodes
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Our study ranges in the biophysics of DNA to synthetic cells and beyond. Please take a look down below within the spectrum of our present-day jobs.
What distinguishes biology from chemistry is the fact that these factors collectively make up a dwelling program. The trick of mentioned everyday living, I believe, lies during the interactions, the interplay of All those molecules. The big problem regarding the origin of everyday living remains unanswered. How did we ever evolve from uncomplicated molecules into the really sophisticated devices we see these days? We don't know. I need to work on these kinds of major, open queries.’
2011, initial in vitro measurements of transport across just one biomimetic nuclear pore complicated; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; ceesdekker.net and resolved the system of homology recognition in DNA homologous recombination
2003, shown the primary biosensors manufactured from a carbon nanotube; resolved the structure and system of DNA repair service proteins; and discovery of a whole new strategy for fabricating sound-state nanopores for DNA translocation
‘The fantastically refined way where aspects in character perform never ceases to amaze me. If we address the puzzle of how everyday living arrived into becoming, I anticipate that my amazement within the complexity of generation will likely have greater and with it my awe to the greatness from the Creator.’
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Additional not too long ago his research has centered on studying chromatin framework and cell division with microorganisms on chip, whilst he is usually trying to finally Create artificial cells from the bottom up.
Nanoscientist Cees Dekker is an amiable and flamboyant man who seems Substantially more youthful compared to 62 many years he actually is – trendy glasses, psychedelic shirt, partaking smile – although not 1 to waste time. He usually takes his time, but not more than required.
2008, to start with observation of protein-coated DNA translocation as a result of nanopores; fixed the origin of your electrophoretic drive on DNA in nanopores; learned an important velocity raise of microtubules in electrical fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
2013, controlled shaping of Stay bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations from the handedness of histone tetrasomes